| Nick Nolte | Thomas Jefferson [L] | |
| Greta Scacchi | Maria Cosway [L] | |
| Jean-Pierre Aumont | D'Hancarville [SR] | |
| Simon Callow | Richard Cosway [SR] | |
| Seth Gilliam | James Hemings [SR] | |
| James Earl Jones | Madison Hemings [SR] | |
| Michael Lonsdale | Louis XVI [SR] | |
| Nancy Marchand | Madame Abbesse [SR] | |
| Thandie Newton | Sally Hemings [SR] | |
| Gwyneth Paltrow | Patsy Jefferson [SR] | |
| Charlotte de Turckheim | Marie Antoinette [SR] | |
| Lambert Wilson | Marquis de Lafayette [SR] | |
| Elsa Zylberstein | Adrienne de Lafayette [SR] | |
| Bruno Putzulu | Figaro [BP] | |
| Vincent Cassel | Camille Desmoulins [BP] | |
| Jack Gomez | Marquis at the King's court | |
